Protecting Livestock. Improving Human Lives

Addressing the Burden of African Animal Trypanosomosis (AAT): The Need for New Solutions for Livestock Keepers

Author: GALVmed

Year: 2025

About this Publication:

The meeting highlighted that whilst AAT remains a solvable problem, it is exacerbated by a critical innovation gap and the failure of current tools under mounting drug resistance and challenging access and distribution pathways. Multi-national collaborations are generating vital data on the socio-economic burden of AAT, informing evidence-based strategies and guiding policy decisions. Regulatory innovations, such as the East African Community’s mutual recognition programme, are improving access to existing tools. However, the need for new, effective solutions remains urgent. The development of novel trypanocides, such as the GALVmed trypanocide development project, represents a critical and timely response to the unmet needs of livestock keepers. Sustained collaboration, advocacy, and prioritisation across the animal health ecosystem are essential to bring these solutions to scale. Key action points emerging from the meeting were: - Advance regulatory harmonization through AU-IBAR and WOAH frameworks to shorten timelines and ensure safe, effective rollout of new medicines. - Strengthen farmer-centric design and stewardship with innovations such as ready-to-use formulations, community engagement models, and robust pharmacovigilance systems. - Mobilize partnerships and investment linking research institutions, policy makers and regulators, private sector, and donors to bridge the innovation gap and position AAT more firmly in national and regional agendas. - Support the GALVmed Trypanocide Initiative by contributing research expertise, clinical trial capacity. The meeting underscored that sustained progress against AAT will require not only technological innovation but also strong, community-driven and cross-sectoral collaboration, anchored by GALVmed’s catalytic role in driving new solutions forward.

Grant: Tryps 3

Subject Areas: Research and Development

Diseases: Trypanosomosis

Countries:

Algeria, Angola, Benin, Botswana, Burkina Faso, Cameroon, Cape Verde, Central African Republic, Chad, Congo, Democratic Republic Of, Congo, Republic Of, Cote D'Ivoire, Egypt, Equatorial Guinea, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Lesotho, Liberia, Libyan Arab Jamahiriya, Mali, Mauritania, Morocco, Namibia, Niger, Nigeria, Saint Helena, Sao Tome And Principe, Senegal, Sierra Leone, South Africa, Sudan, Swaziland, Togo, Tunisia, Western Sahara

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