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Sequence diversity of cytotoxic T cell antigens and satellite marker analysis of Theileria parva informs the immunization against East Coast fever in Rwanda

Author: David Kalenzi Atuhaire, Walter Muleya , Victor Mbao, Thomas Bazarusanga, Isidore Gafarasi, Jeremy Salt, Boniface Namangala, Antony Jim Musoke

Year: 2020

About this Publication:

East Coast fever (ECF) caused by Theileria parva is endemic in Rwanda. In this study, the antigenic and genetic diversity of T. parva coupled with immunization and field challenge were undertaken to provide evidence for the introduction of ECF immunization in Rwanda.

Grant: PLSHL2

Subject Areas: Research and Development

Diseases: East Coast Fever

URL https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-020-04322-9

Keywords:

ECF, Immunization, Muguga cocktail, Sub-structuring, Theileria parva, Tp1, Tp2

Countries:

Rwanda

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