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Repositioning of a diaminothiazole series confirmed to target the cyclin-dependent kinase CRK12 for use in the treatment of African animal trypanosomiasis.

Author: Smith A, Wall RJ, Patterson S, Rowan T, Vida ER, Stojanovski L, Huggett M, Hampton SE, Thomas MG, Lopez VC, Gillingwater K, Duke J, Napier G, Peter R, Vitouley HS, Harrison JR, Milne R, Jeacock L, Baker N, Davis SH, Simeons F, Riley J, Horn D, Brun R, Zuccotto F, Witty MJ, Wyllie S, Read KD, Gilbert IH.

Year: 2022

Subject Areas: Research and Development

Keywords: African animal trypanosomiasis diaminothiazole