Publications

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Identification of a 4-fluorobenzyl L-valinate amide benzoxaborole (AN11736) as a potential development candidate for the treatment of Animal African Trypanosomiasis (AAT)

Author: Tsutomu Akama, Yong-Kang Zhang, Yvonne R. Freund, Pamela Berry, Joanne Lee, Eric E. Easom, Robert T. Jacobs, Jacob J. Plattner, Michael J. Witty, Rosemary Peter, Tim G. Rowan, Kirsten Gillingwater, Reto Brun, Bakela Nare, Luke Mercer, Musheng Xu, Jiangong Wang, Hao Liang

Year: 2017

Subject Areas: Research and Development

Keywords: AAT, African African Trypanosomosis, Benzoxaborole, Cattle, Lead optimisation, Protozoan, R&D, SAR, Trypanosomiasis, Trypanosomosis ...plus 2 more

AN11736, A Benzoxaborole Clinical Candidate for Treatment of T.congolense and T. vivax African Animal Trypanosomosis

Author: Yvonne R. Freund, Tsutomu Akama, Pamela Berry, Yong-Kang Zhang, Eric Easom, Robert T. Jacobs, Jacob J. Plattner, Michael Witty, Tim Rowan, Rosemary Peter

Year: 2016

Subject Areas: Research and Development

Keywords: Trypanosomosis, african animal trypanosomosis, anacor, clinical candidate, t congolense, t vivax

Ethiopia Field Study Report on Animal African Trypanosomosis

Author: Hannah Holt, Bhagyalakshmi Chengat Prakashbabu, Morgane Salines, Richard Selby, Grant Napier and Javier Guitan

Year: 2016

Subject Areas: Research and Development

Keywords: Animal African Trypanosomosis, Animal African trypanosomiasis, Cattle, Sub-Saharan Africa, Trypanosomosis, Tryps, Tsetse

Uganda Field Study Report on Animal African Trypanosomosis

Author: Morgane Salines, Richard Selby, Charles Waiswa, Hannah Holt, Grant Napier and Javier Guitian

Year: 2016

Subject Areas: Research and Development

Keywords: Animal African Trypanosomosis, Animal African trypanosomiasis, Cattle, Sub-Saharan Africa, Trypanosomosis, Tryps, Tsetse

Zambia Field Study Report on Animal African Trypanosomosis

Author: Hannah Holt, Chisoni Mumba, Morgane Salines, Richard Selby, Grant Napier and Javier Guitian

Year: 2016

Subject Areas: Research and Development

Keywords: Animal African Trypanosomosis, Animal African trypanosomiasis, Cattle, Sub-Saharan Africa, Trypanosomosis, Tryps, Tsetse

Burkina Faso Field Study Report on Animal African Trypanosomosis

Author: Morgane Salines, Hannah Holt, Richard Selby, Bhagyalakshmi Chengat Prakashbabu, Grant Napier and Javier Guitian

Year: 2016

Subject Areas: Research and Development

Keywords: Animal African Trypanosomosis, Animal African trypanosomiasis, Cattle, Sub-Saharan Africa, Trypanosomosis, Tryps, Tsetse, Vulnerability assessment

The animal trypanosomiases and their chemotherapy: A review

Author: Federica Giordani, Liam J. Morrison, Tim G. Rowan, Harry P. De Koning and Michael P. Barrett

Year: 2016

Subject Areas: Research and Development

Keywords: Trypanosoma brucei, Trypanosoma congolense, Trypanosoma vivax, animal trypanosomiases, drug resistance, veterinary trypanocide

Anamnestic responses in pigs to the Taenia solium TSOL18 vaccine and implications for control strategies

Author: Lightowlers MW, Donadeu M, Elaiyaraja M, Maithal K, Kumar KA, Gauci CG, Firestone SM, Sarasola P, Rowan TG

Year: 2016

Subject Areas: Research and Development

Keywords: Pig, TSOL18, Taenia solium, Vaccine, anamnestic response

Identification of trans-sialidases as a common mediator of endothelial cell activation by African trypanosomes

Author: Zeinab Ammar, Nicolas Plazolles,Théo Baltz,Virginie Coustou. GALVmed and DFID acknowledged.

Year: 2013

Subject Areas: Research and Development

Keywords: Trypanosomosis

Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake

Author: Jane C. Munday, Karla E. Rojas López, Anthonius A. Eze, Vincent Delespaux, Jan Van Den Abbeele, Tim Rowan, Michael P. Barrett, Liam J. Morrison and Harry P. de Koning

Year: 2012

Subject Areas: Research and Development

Keywords: Trypanosomosis,

Community- and farmer-based management of animal African trypanosomosis in cattle

Author: Jérémy Bouyer, Fanny Bouyer, Meritxell Donadeu, Tim Rowan, Grant Napier. GALVmed and DFID acknowledged.

Year: 2013

Subject Areas: Policy and Advocacy, Research and Development

Keywords: Disease Control, Trypanosomosis, Tsetse