Publications

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Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

Author: Federica Giordani, Daniel Paape, Isabel M. Vincent, Andrew W. Pountain, Fernando Fernández-Cortés, Eva Rico, Ning Zhang, Liam J. Morrison, Yvonne Freund, Michael J. Witty, Rosemary Peter, Darren Y. Edwards, Jonathan M. Wilkes, Justin J. J. van der Hooft, Clément Regnault, Kevin D. Read, David Horn, Mark C. Field, Michael P. Barrett

Year: 2020

Subject Areas: Research and Development

Keywords: T. brucei, T. vivax, Trypanocidal benzoxaboroles, Trypanosoma congolense

TSOL18 vaccine and oxfendazole for control of Taenia solium cysticercosis in pigs: A field trial in endemic areas of Tanzania

Author: Mwemezi L. Kabululu, Helena A. Ngowi, James E. D. Mlangwa, Ernatus M. Mkupasi, Uffe C. Braae, Angela Colston, Claudia Cordel, Elizabeth J. Poole, Kristin Stuke, Maria V. Johansen

Year: 2020

Subject Areas: Research and Development

Keywords: Oxfendazole, Pigs, T. solium cysticercosis, TSOL18, Taenia solium, Tanzania

Performance of Ag-ELISA in the diagnosis of Taenia solium cysticercosis in naturally infected pigs in Tanzania

Author: Mwemezi L. Kabululu, Maria V. Johansen, James E. D. Mlangwa, Ernatus M. Mkupasi, Uffe C. Braae, Chiara Trevisan, Angela Colston, Claudia Cordel, Marshall W. Lightowlers, Helena A. Ngowi

Year: 2020

Subject Areas: Research and Development

Keywords: Ag-ELISA, Diagnosis, Pigs, Taenia solium, Tanzania

Endemicity of Taenia solium cysticercosis in pigs from Mbeya Rural and Mbozi districts, Tanzania

Author: Mwemezi L. Kabululu, Helena A. Ngowi, James E. D. Mlangwa, Ernatus M. Mkupasi, Uffe C. Braae, Chiara Trevisan, Angela Colston, Claudia Cordel & Maria V. Johansen

Year: 2020

Subject Areas: Research and Development

Keywords: Porcine Cysticercosis, Prevalence, Taenia solium, Tanzania, taeniasis

Sequence diversity of cytotoxic T cell antigens and satellite marker analysis of Theileria parva informs the immunization against East Coast fever in Rwanda

Author: David Kalenzi Atuhaire, Walter Muleya , Victor Mbao, Thomas Bazarusanga, Isidore Gafarasi, Jeremy Salt, Boniface Namangala, Antony Jim Musoke

Year: 2020

Subject Areas: Research and Development

Keywords: ECF, Immunization, Muguga cocktail, Sub-structuring, Theileria parva, Tp1, Tp2

Potential Elimination of Active Taenia solium Transmission in Africa

Author: Sarah Gabriël, Kabemba E. Mwape, Emma C. Hobbs, Brecht Devleesschauwer, Inge Van Damme, Gideon Zulu, Chembensofu Mwelwa, Moses Mambwe, Tine De Coster, Isaac K. Phiri, Dirk L. Berkvens, Angie Colston, Emmanuel Bottieau, Niko Speybroeck, Jennifer K. Ketzis, Chiara Trevisan

Year: 2020

Subject Areas: Research and Development

Keywords: Africa, Porcine Cysticercosis, Taenia solium

Contagious Bovine and Caprine Pleuropneumonia: a research community’s recommendations for the development of better vaccines

Author: Joerg Jores, Cynthia Baldwin , Alain Blanchard , Glenn F. Browning , Angie Colston , Volker Gerdts , Danny Goovaerts , Martin Heller , Nick Juleff , Fabien Labroussaa , Anne Liljander , Geoffrey Muuka, Vish Nene , Ran Nir-Paz, Flavio Sacchini, Artur Summerfield, François Thiaucourt, Hermann Unger, Sanjay Vashee, Xiumei Wang and Jeremy Salt

Year: 2020

Subject Areas: Research and Development

Keywords: Contagious Bovine Pleuropneumonia, Contagious Caprine Pleuropneumonia

Protection of Cattle Elicited Using a Bivalent Lumpy Skin Disease Virus-Vectored Recombinant Rift Valley Fever Vaccine

Author: D.B Wallace, A. Mather1, P. D. Kara, Leeann Naicker, Nobalanda B. Mokoena, A. Pretorius, T. Nefefe, N. Thema and Shawn Babiuk

Year: 2020

Subject Areas: Research and Development

Keywords: Capripoxviruses, ELISA, PCR, RNA virus, Vaccination, candidate vaccine, challenge, recombination

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

Author: Daniela Begolo, Isabel M. Vincent,Federica Giordani,Ina Pöhner,Michael J. Witty,Timothy G. Rowan,Zakaria Bengaly,Kirsten Gillingwater,Yvonne Freund,Rebecca C. Wade,Michael P. Barrett,Christine Clayton

Year: 2018

Subject Areas: Research and Development

Keywords: AAT, African African Trypanosomosis, Benzoxaborole, Cattle, Protozoan, R&D, RNA, Resistance, Trypanosomiasis, Tryps ...plus 1 more

Mmm-derived lipid-associated membrane proteins activate IL-1? production through the NF-?B pathway via TLR2, MyD88, and IRAK4

Author: Yang Wang, Qi Wang, Yuan Li, Ying Chen, Jiari Shao, Nwankpa Nick, Chunyan Li & Jiuqing Xin

Year: 2017

Subject Areas: Research and Development

An analysis of the impact of Newcastle disease vaccination and husbandry practice on smallholder chicken productivity in Uganda

Author: Paul Bessell, Roy Woolley, Stuart Stevenson, Lamyaa Al-Riyami, Patrick Opondo, Leslie Lai and Neil Gammon

Year: 2020

Subject Areas: Monitoring and Evaluation

Keywords: Chickens, Husbandry, Newcastle Disease, Productivity, Smallholder, Vaccination

Accurate diagnosis of lesions suspected of being caused by Taenia solium in body organs of pigs with naturally acquired porcine cysticercosis

Author: Charles G. Gauci,Chrisostom Ayebazibwe,Zachary Nsadha,Chris Rutebarika,Ishab Poudel,Keshav Sah,Dinesh Kumar Singh,Andrew Stent,Angela Colston,Meritxell Donadeu,Marshall W. Lightowlers

Year: 2019

Subject Areas: Research and Development

Keywords: Porcine Cysticercosis, Taenia solium, body organs, cysticerci

Implementation of a practical and effective pilot intervention against transmission of Taenia solium by pigs in the Banke district of Nepal

Author: Ishab Poudel, Keshav Sah , Suyog Subedi , Dinesh Kumar Singh , Peetambar Kushwaha , Angela Colston , Charles G. Gauci , Meritxell Donadeu , Marshall W. Lightowlers

Year: 2019

Subject Areas: Research and Development

Keywords: Nepal, Porcine Cysticercosis, Taenia solium

Perceptions and acceptability of piloted Taenia solium control and elimination interventions in two endemic communities in eastern Zambia

Author: Emma Clare Hobbs| Kabemba Evans Mwape | Andrew M. Phiri | Moses Mambwe | Richard Mambo | Séverine Thys | Gideon Zulu | Mwelwa Chembensofu| Chiara Trevisan | Inge Van Damme | Isaac Khozozo Phiri | Brecht Devleesschauwer | Jennifer Ketzis | Pierre Dorny | Arve Lee Willingham | Sarah Gabriël

Year: 2019

Subject Areas: Research and Development

Keywords: Taenia solium, communicable disease control, focus groups, parasites, public health, surveys and questionnaires

Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia

Author: T. Tekle, G. Terefe , T. Cherenet, H. Ashenafi, K. G. Akoda, A. Teko-Agbo, J. Van Den Abbeele, G. Gari, P.-H. Clausen, A. Hoppenheit, R. C. Mattioli, R. Peter, T. Marcotty, G. Cecchi and V. Delespaux

Year: 2018

Subject Areas: Research and Development

Keywords: Diminazene, Drug quality assessment, Drug utilization practice, Ethiopia, Isometamidium, Trypanocide

A market scoping study for porcine cysticercosis vaccine calls for a one-health approach to sustain the control of the disease in Uganda

Author: Michel Dione, Adediran Adeniyi Samuel, Angie Colston, Emily Ouma, Peter Lule and Delia Grace

Year: 2019

Subject Areas: Policy and Advocacy

Keywords: PC, Porcine Cysticercosis, onehealth

The impact of anthelmintic drugs on weight gain of smallholder goats in subtropical regions

Author: Paul R.Bessell, Neil D.Sargison, Kichuki Mirende, Ranjit Dash, Sanjay Prasad, Lamyaa Al-Riyami, Neil Gammon, Kristin Stuke, Roy Woolley, Miftahul Barbaruah and PhilemonWambur

Year: 2018

Subject Areas: Monitoring and Evaluation

Keywords: M&E, Smallholder, anthelminthic, drugs, goats