Protecting Livestock. Improving Human Lives

Trypanosoma vivax GM6 Antigen: A Candidate Antigen for Diagnosis of African Animal Trypanosomosis in Cattle

Author: Pillay D, Izotte J, Fikru R, Buscher P, Mucache H, Neves L, Boulange A, Seck MT, Bouyer J, Napier GB, Chevtzoff C, Costou V, Baltz T

Year: 2013

About this Publication:

Diagnosis of African animal trypanosomosis is vital to controlling this severe disease which hampers development across 10 million km2 of Africa endemic to tsetse flies. Diagnosis at the point of treatment is currently dependent on parasite detection which is unreliable, and on clinical signs, which are common to several other prevalent bovine diseases. This study is the first to analyse the GM6 antigen of T. vivax and the first to test the GM6 antigen on a large collection of sera from experimentally and naturally infected cattle. This study demonstrates that the TvGM6 is an excellent candidate antigen for the development of a point-of-treatment test for diagnosis of T. vivax, and to a lesser extent T. congolense, African animal trypanosomosis in cattle.

Grant: Tryps1

Subject Areas: Research and Development

Diseases: Trypanosomosis

Keywords:

Diagnosis, Trypanosomosis

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