Protecting Livestock. Improving Human Lives

The control of East Coast fever of cattle by live parasite vaccination: A science-to-impact narrative

Author: B.D. Perry

Year: 2016

About this Publication:

There is an increasing interest in determining the impact of vaccine technologies developed using public funding targeted at international development, and understanding the factors and ingredients which contribute to the success and impacts of such vaccines. This paper chronicles the development of a live vaccine against East Coast fever, a tick-borne disease of cattle caused by Theileria parva. The paper describes the technological innovation, commonly known as infection-and-treatment, which was developed some 40 years ago, explores the institutional settings in which the vaccinewas developed and refined, and discusses the political dynamics of both during the decades from first development to field deployment and impacts. The paper also analyses the direct and indirect indicators of success of ITM and the many qualifiers of these, the impacts that the emerging technology has had, both in positive and negative terms, and maps the key contributors and milestones on the research-to-impact pathway

Grant: PLSHL2

Subject Areas: Research and Development

Diseases: East Coast Fever


ECF, East Coast Fever, Theileria, Vaccination, Vaccine, ticks

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