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Antimicrobial susceptibility testing of Mycoplasma mycoides subspecies mycoides isolates recovered from tissues of control and treated cattle from cattle following controlled antimicrobial treatment trials

Author: Anne Ridley, Geoffrey Muuka, Hezron Wesonga, Roger Ayling, Jane Plater, Nimmo Gicheru, Stuke, K., Colston, A., Salt J.

Year: 2022

About this Publication:

Two previously reported studies in Kenya and Zambia demonstrated that oxytetracycline, tulathromycin or gamithromycin treatment, following infection via an in-contact disease transmission of cattle with Mycoplasma mycoides subsp. mycoides (Mmm), significantly reduced clinical signs, mortality, tissue lesions and spread of infection to susceptible cattle. However, with the exception of tulathromycin-treated cattle in Kenya, bacteriological clearance of Mmm was incomplete, with recovery of the organism from a minority of treated animals. In the present study, Mmm cultures from these cattle were transported to the Animal and Plant Health Agency and revived for susceptibility testing against twelve veterinary therapeutic antibiotics, including those used as treatment.

Grant: PLSHL2

Subject Areas: Research and Development

Diseases: Contagious Bovine Pleuropneumonia


Antibiotic, Contagious bovine pleuropneumonia (CBPP), Mycoplasma mycoides subsp. mycoides, minimum inhibitory concentration (MIC), susceptibility


Kenya, Zambia

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